Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
Viruses infect cells mainly via specific receptors at the cell surface. Antibody-dependent enhancement (ADE) of infection is an alternative mechanism of infection for viruses to infect immune cells that is mediated by antibodies and IgG receptors (FcγRs).
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Main Authors: | Tadashi Maemura, Makoto Kuroda, Tammy Armbrust, Seiya Yamayoshi, Peter J. Halfmann, Yoshihiro Kawaoka |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2021
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Online Access: | https://doaj.org/article/12e3490708e448ae89ca43a7164d8f6e |
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