BH3-only proteins Puma and Beclin1 regulate autophagic death in neurons in response to Amyloid-β
Abstract Alzheimer’s disease (AD) is characterized by accumulation of senile amyloid-β (Aβ) plaques and hyperphosphorylated tau tangles causing progressive loss of synapse and neuronal death. Out of the various neuron death modalities, autophagy and apoptosis are reported to be the major death parad...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Publishing Group
2021
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| Accès en ligne: | https://doaj.org/article/131fddba260544bba6cd6f9e074fe80b |
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