Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor

ABSTRACT Microcin C (McC) is a peptide adenylate antibiotic produced by Escherichiacoli cells bearing a plasmid-borne mcc gene cluster. Most MccA precursors, encoded by validated mcc operons from diverse bacteria, are 7 amino acids long, but the significance of this precursor length conservation has...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Inna Zukher, Michael Pavlov, Darya Tsibulskaya, Alexey Kulikovsky, Tatyana Zyubko, Dmitry Bikmetov, Marina Serebryakova, Satish K. Nair, Måns Ehrenberg, Svetlana Dubiley, Konstantin Severinov
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://doaj.org/article/1320d8f1afa64361aa8de0fbe621008b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!