Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

Modelling oral squamous cell carcinoma (OSCC) is a complex endeavour. Here, the authors provide a comprehensive analysis of an OSCC mouse model and show its mutational signatures mirror human OSCC, providing insights into OSCC clonal dynamics, the microenvironment and evolution.

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Detalles Bibliográficos
Autores principales: Inês Sequeira, Mamunur Rashid, Inês M. Tomás, Marc J. Williams, Trevor A. Graham, David J. Adams, Alessandra Vigilante, Fiona M. Watt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/13283850aaeb488c9ff3f4816f9ef00d
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