Leucine imparts cardioprotective effects by enhancing mTOR activity and mitochondrial fusion in a myocardial ischemia/reperfusion injury murine model

Leucine imparts cardioprotective effects by enhancing mTOR activity and mitochondrial fusion in a myocardial ischemia/reperfusion injury murine model

Abstract Background Coronary artery disease is a leading cause of morbidity and mortality among patients with diabetes. Previously, we demonstrated that branched-chain amino acids (BCAAs) showed cardioprotective effects against cardiac ischemia/reperfusion (I/R) injury. A recent study suggested that...

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Autores principales: Atsushi Morio, Rie Tsutsumi, Shiho Satomi, Takashi Kondo, Hirotsugu Miyoshi, Takahiro Kato, Masashi Kuroda, Tadahiro Kitamura, Kenta Hara, Noboru Saeki, Hiroshi Sakaue, Yasuo M. Tsutsumi
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Leucine
High-fat diet
Myocardial ischemia/reperfusion injury
Cardioprotective
Nutritional diseases. Deficiency diseases
RC620-627
Acceso en línea:https://doaj.org/article/13539f8798bd470098c79f5c743f524b
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https://doaj.org/article/13539f8798bd470098c79f5c743f524b

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