Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors

Double conditional knockout of Meis1/2 in the limb forming region of mouse embryos results in the complete absence of limb, while embryos developed with one functional Meis allele, so identifying the role of Meis in antero-posterior and proximo-distal patterning.

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Auteurs principaux: Irene Delgado, Giovanna Giovinazzo, Susana Temiño, Yves Gauthier, Aurelio Balsalobre, Jacques Drouin, Miguel Torres
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/136e8a5b878340a4a8a9d68369c89483
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