Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors

Double conditional knockout of Meis1/2 in the limb forming region of mouse embryos results in the complete absence of limb, while embryos developed with one functional Meis allele, so identifying the role of Meis in antero-posterior and proximo-distal patterning.

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Autores principales:	Irene Delgado, Giovanna Giovinazzo, Susana Temiño, Yves Gauthier, Aurelio Balsalobre, Jacques Drouin, Miguel Torres
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/136e8a5b878340a4a8a9d68369c89483
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spelling	oai:doaj.org-article:136e8a5b878340a4a8a9d68369c894832021-12-02T14:42:19ZControl of mouse limb initiation and antero-posterior patterning by Meis transcription factors10.1038/s41467-021-23373-92041-1723https://doaj.org/article/136e8a5b878340a4a8a9d68369c894832021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23373-9https://doaj.org/toc/2041-1723Double conditional knockout of Meis1/2 in the limb forming region of mouse embryos results in the complete absence of limb, while embryos developed with one functional Meis allele, so identifying the role of Meis in antero-posterior and proximo-distal patterning.Irene DelgadoGiovanna GiovinazzoSusana TemiñoYves GauthierAurelio BalsalobreJacques DrouinMiguel TorresNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Irene Delgado Giovanna Giovinazzo Susana Temiño Yves Gauthier Aurelio Balsalobre Jacques Drouin Miguel Torres Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
description	Double conditional knockout of Meis1/2 in the limb forming region of mouse embryos results in the complete absence of limb, while embryos developed with one functional Meis allele, so identifying the role of Meis in antero-posterior and proximo-distal patterning.
format	article
author	Irene Delgado Giovanna Giovinazzo Susana Temiño Yves Gauthier Aurelio Balsalobre Jacques Drouin Miguel Torres
author_facet	Irene Delgado Giovanna Giovinazzo Susana Temiño Yves Gauthier Aurelio Balsalobre Jacques Drouin Miguel Torres
author_sort	Irene Delgado
title	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
title_short	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
title_full	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
title_fullStr	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
title_full_unstemmed	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors
title_sort	control of mouse limb initiation and antero-posterior patterning by meis transcription factors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/136e8a5b878340a4a8a9d68369c89483
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Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors

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