Mapping the kinetic barriers of a Large RNA molecule's folding landscape.

The folding of linear polymers into discrete three-dimensional structures is often required for biological function. The formation of long-lived intermediates is a hallmark of the folding of large RNA molecules due to the ruggedness of their energy landscapes. The precise thermodynamic nature of the...

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Autores principales: Jörg C Schlatterer, Joshua S Martin, Alain Laederach, Michael Brenowitz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/1396c9de73b34f869f75aa23b2caea99
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