An engineered channelrhodopsin optimized for axon terminal activation and circuit mapping

Hamada et al. engineer and utilise a channelrhodopsin-2 variant that is localized to presynaptic axon terminals. They demonstrate its use for circuitry mapping in vivo and thus provide a useful tool for future optogenetic experiments

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Autores principales: Shun Hamada, Masashi Nagase, Tomohiko Yoshizawa, Akari Hagiwara, Yoshikazu Isomura, Ayako M. Watabe, Toshihisa Ohtsuka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/13bb96c2e73745bfae399a7b886c98d7
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