Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation
Prokaryotic translation initiation involves mRNA-ribosomal RNA base pairing interactions. Here, the authors provide evidence for a similar base pairing interactions occurring between the human h4 mRNA and helix 16 of the small subunit rRNA to position the correct AUG codon in the decoding site.
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Main Authors: | Franck Martin, Jean-François Ménétret, Angelita Simonetti, Alexander G. Myasnikov, Quentin Vicens, Lydia Prongidi-Fix, S. Kundhavai Natchiar, Bruno P. Klaholz, Gilbert Eriani |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/13bf703b19f34a32b972880d5c0ed24e |
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