Hierarchical nanostructure and synergy of multimolecular signalling complexes

Imaging the nanostructure of signalling complexes in cells is challenging. Here, the authors present a multicolour, single-molecule, super-resolution approach with statistical tools to reveal a hierarchical topology and synergy of signalling complexes downstream of the T-cell receptor in fixed and l...

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Autores principales: Eilon Sherman, Valarie A. Barr, Robert K. Merrill, Carole K. Regan, Connie L. Sommers, Lawrence E. Samelson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/13ef84514ec6495aa1fd7ae991fc680e
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