Hierarchical nanostructure and synergy of multimolecular signalling complexes

Imaging the nanostructure of signalling complexes in cells is challenging. Here, the authors present a multicolour, single-molecule, super-resolution approach with statistical tools to reveal a hierarchical topology and synergy of signalling complexes downstream of the T-cell receptor in fixed and l...

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Autores principales:	Eilon Sherman, Valarie A. Barr, Robert K. Merrill, Carole K. Regan, Connie L. Sommers, Lawrence E. Samelson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/13ef84514ec6495aa1fd7ae991fc680e
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spelling	oai:doaj.org-article:13ef84514ec6495aa1fd7ae991fc680e2021-12-02T15:35:23ZHierarchical nanostructure and synergy of multimolecular signalling complexes10.1038/ncomms121612041-1723https://doaj.org/article/13ef84514ec6495aa1fd7ae991fc680e2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12161https://doaj.org/toc/2041-1723Imaging the nanostructure of signalling complexes in cells is challenging. Here, the authors present a multicolour, single-molecule, super-resolution approach with statistical tools to reveal a hierarchical topology and synergy of signalling complexes downstream of the T-cell receptor in fixed and live cells.Eilon ShermanValarie A. BarrRobert K. MerrillCarole K. ReganConnie L. SommersLawrence E. SamelsonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eilon Sherman Valarie A. Barr Robert K. Merrill Carole K. Regan Connie L. Sommers Lawrence E. Samelson Hierarchical nanostructure and synergy of multimolecular signalling complexes
description	Imaging the nanostructure of signalling complexes in cells is challenging. Here, the authors present a multicolour, single-molecule, super-resolution approach with statistical tools to reveal a hierarchical topology and synergy of signalling complexes downstream of the T-cell receptor in fixed and live cells.
format	article
author	Eilon Sherman Valarie A. Barr Robert K. Merrill Carole K. Regan Connie L. Sommers Lawrence E. Samelson
author_facet	Eilon Sherman Valarie A. Barr Robert K. Merrill Carole K. Regan Connie L. Sommers Lawrence E. Samelson
author_sort	Eilon Sherman
title	Hierarchical nanostructure and synergy of multimolecular signalling complexes
title_short	Hierarchical nanostructure and synergy of multimolecular signalling complexes
title_full	Hierarchical nanostructure and synergy of multimolecular signalling complexes
title_fullStr	Hierarchical nanostructure and synergy of multimolecular signalling complexes
title_full_unstemmed	Hierarchical nanostructure and synergy of multimolecular signalling complexes
title_sort	hierarchical nanostructure and synergy of multimolecular signalling complexes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/13ef84514ec6495aa1fd7ae991fc680e
work_keys_str_mv	AT eilonsherman hierarchicalnanostructureandsynergyofmultimolecularsignallingcomplexes AT valarieabarr hierarchicalnanostructureandsynergyofmultimolecularsignallingcomplexes AT robertkmerrill hierarchicalnanostructureandsynergyofmultimolecularsignallingcomplexes AT carolekregan hierarchicalnanostructureandsynergyofmultimolecularsignallingcomplexes AT connielsommers hierarchicalnanostructureandsynergyofmultimolecularsignallingcomplexes AT lawrenceesamelson hierarchicalnanostructureandsynergyofmultimolecularsignallingcomplexes
_version_	1718386580056440832

Hierarchical nanostructure and synergy of multimolecular signalling complexes

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