Clathrin adapters AP-1 and GGA2 support expression of epidermal growth factor receptor for cell growth
Abstract The role of Golgi/endosome-localized clathrin adapters in the maintenance of steady-state cell surface epidermal growth factor receptor (EGFR) is not well known. Here, we show that EGFR associates preferentially with both AP-1 and GGA2 in vitro. AP-1 depletion caused a reduction in the EGFR...
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Autores principales: | Takefumi Uemura, Takehiro Suzuki, Naoshi Dohmae, Satoshi Waguri |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
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Acceso en línea: | https://doaj.org/article/141cef8827ce44c189674d485234760b |
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