Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan

Abstract The intrinsic aerobic capacity of an organism is thought to play a role in aging and longevity. Maximal respiratory rate capacity, a metabolic performance measure, is one of the best predictors of cardiovascular- and all-cause mortality. Rats selectively bred for high-(HCR) vs. low-(LCR) in...

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Auteurs principaux: Miguel A. Aon, Sonia Cortassa, Magdalena Juhaszova, José A. González-Reyes, Miguel Calvo-Rubio, José M. Villalba, Andrew D. Lachance, Bruce D. Ziman, Sarah J. Mitchell, Kelsey N. Murt, Jessie E. C. Axsom, Irene Alfaras, Steven L. Britton, Lauren G. Koch, Rafael de Cabo, Edward G. Lakatta, Steven J. Sollott
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/14634003ef5e447c891b439fccd94408
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