The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism

RecQ helicases are important for maintaining genomic integrity. Here, the authors present functional data and the crystal structure of human RecQ4, which exerts a helicase mechanism that may be more closely related to bacterial RecQ helicases than to its human family members.

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Autores principales: Sebastian Kaiser, Florian Sauer, Caroline Kisker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/147d31ce692b44a8aba126cc52fb6e05
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