Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer

The progression from biliary tract intraepithelial neoplasia (BilIN) to gallbladder carcinoma (GBC) remains unclear. Here the authors use genomics to analyze coexisting GBC lesions, low-grade and high-grade BilINs, revealing two distinct evolutionary paths for GBC development.

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Autores principales: Jianzhen Lin, Xinxin Peng, Kun Dong, Junyu Long, Xuejiao Guo, Hongyue Li, Yi Bai, Xu Yang, Dongxu Wang, Xin Lu, Yilei Mao, Xinting Sang, Xuwo Ji, Haitao Zhao, Han Liang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/148932c71cdc4be3a5257b88f4baf168
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