REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion

The repressor-element 1-silencing transcription/neuron-restrictive silencer factor (REST/NRSF) controls hundreds of neuron-specific genes. We showed that REST/NRSF downregulates glutamatergic transmission in response to hyperactivity, thus contributing to neuronal homeostasis. However, whether GABAe...

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Bibliographic Details
Main Authors: Cosimo Prestigio, Daniele Ferrante, Antonella Marte, Alessandra Romei, Gabriele Lignani, Franco Onofri, Pierluigi Valente, Fabio Benfenati, Pietro Baldelli
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/14914593879644449fe8f7f3e92e6cdc
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