Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease

Diurnal and seasonal rhythms modulate brain function, but we do not know the genomic basis for these rhythms. Here, Limet al. show diurnal and seasonal rhythms of gene expression in the human brain, their relationship to histone acetylation and DNA methylation, and their disruption in Alzheimer’s di...

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Auteurs principaux: Andrew S. P. Lim, Hans-Ulrich Klein, Lei Yu, Lori B. Chibnik, Sanam Ali, Jishu Xu, David A. Bennett, Philip L. De Jager
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/14a25e9a537c4859a2ce013c645327f1
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