Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease

Diurnal and seasonal rhythms modulate brain function, but we do not know the genomic basis for these rhythms. Here, Limet al. show diurnal and seasonal rhythms of gene expression in the human brain, their relationship to histone acetylation and DNA methylation, and their disruption in Alzheimer’s di...

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Autores principales:	Andrew S. P. Lim, Hans-Ulrich Klein, Lei Yu, Lori B. Chibnik, Sanam Ali, Jishu Xu, David A. Bennett, Philip L. De Jager
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/14a25e9a537c4859a2ce013c645327f1
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spelling	oai:doaj.org-article:14a25e9a537c4859a2ce013c645327f12021-12-02T15:38:37ZDiurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease10.1038/ncomms149312041-1723https://doaj.org/article/14a25e9a537c4859a2ce013c645327f12017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14931https://doaj.org/toc/2041-1723Diurnal and seasonal rhythms modulate brain function, but we do not know the genomic basis for these rhythms. Here, Limet al. show diurnal and seasonal rhythms of gene expression in the human brain, their relationship to histone acetylation and DNA methylation, and their disruption in Alzheimer’s disease.Andrew S. P. LimHans-Ulrich KleinLei YuLori B. ChibnikSanam AliJishu XuDavid A. BennettPhilip L. De JagerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrew S. P. Lim Hans-Ulrich Klein Lei Yu Lori B. Chibnik Sanam Ali Jishu Xu David A. Bennett Philip L. De Jager Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease
description	Diurnal and seasonal rhythms modulate brain function, but we do not know the genomic basis for these rhythms. Here, Limet al. show diurnal and seasonal rhythms of gene expression in the human brain, their relationship to histone acetylation and DNA methylation, and their disruption in Alzheimer’s disease.
format	article
author	Andrew S. P. Lim Hans-Ulrich Klein Lei Yu Lori B. Chibnik Sanam Ali Jishu Xu David A. Bennett Philip L. De Jager
author_facet	Andrew S. P. Lim Hans-Ulrich Klein Lei Yu Lori B. Chibnik Sanam Ali Jishu Xu David A. Bennett Philip L. De Jager
author_sort	Andrew S. P. Lim
title	Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease
title_short	Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease
title_full	Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease
title_fullStr	Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease
title_full_unstemmed	Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease
title_sort	diurnal and seasonal molecular rhythms in human neocortex and their relation to alzheimer’s disease
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/14a25e9a537c4859a2ce013c645327f1
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Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease

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