Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae

Antimicrobial resistance is a global health challenge. Few new antibiotics have been developed for use over the years, and preserving the efficacy of existing compounds is an important step to protect public health. This paper describes a study that examines the effects of exogenously induced oxid...

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Autores principales: João Anes, Katherine Dever, Athmanya Eshwar, Scott Nguyen, Yu Cao, Sathesh K. Sivasankaran, Sandra Sakalauskaitė, Angelika Lehner, Stéphanie Devineau, Rimantas Daugelavičius, Roger Stephan, Séamus Fanning, Shabarinath Srikumar
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/14a94f637a5743119c7891bd75fb49a9
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spelling oai:doaj.org-article:14a94f637a5743119c7891bd75fb49a92021-11-03T21:15:03Z Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae 2150-751110.1128/mBio.00867-21https://doaj.org/article/14a94f637a5743119c7891bd75fb49a92021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00867-21https://doaj.org/toc/2150-7511 Antimicrobial resistance is a global health challenge. Few new antibiotics have been developed for use over the years, and preserving the efficacy of existing compounds is an important step to protect public health. This paper describes a study that examines the effects of exogenously induced oxidative stress on K. pneumoniaeJoão AnesKatherine DeverAthmanya EshwarScott NguyenYu CaoSathesh K. SivasankaranSandra SakalauskaitėAngelika LehnerStéphanie DevineauRimantas DaugelavičiusRoger StephanSéamus FanningShabarinath SrikumarAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
João Anes
Katherine Dever
Athmanya Eshwar
Scott Nguyen
Yu Cao
Sathesh K. Sivasankaran
Sandra Sakalauskaitė
Angelika Lehner
Stéphanie Devineau
Rimantas Daugelavičius
Roger Stephan
Séamus Fanning
Shabarinath Srikumar
Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
description Antimicrobial resistance is a global health challenge. Few new antibiotics have been developed for use over the years, and preserving the efficacy of existing compounds is an important step to protect public health. This paper describes a study that examines the effects of exogenously induced oxidative stress on K. pneumoniae
format article
author João Anes
Katherine Dever
Athmanya Eshwar
Scott Nguyen
Yu Cao
Sathesh K. Sivasankaran
Sandra Sakalauskaitė
Angelika Lehner
Stéphanie Devineau
Rimantas Daugelavičius
Roger Stephan
Séamus Fanning
Shabarinath Srikumar
author_facet João Anes
Katherine Dever
Athmanya Eshwar
Scott Nguyen
Yu Cao
Sathesh K. Sivasankaran
Sandra Sakalauskaitė
Angelika Lehner
Stéphanie Devineau
Rimantas Daugelavičius
Roger Stephan
Séamus Fanning
Shabarinath Srikumar
author_sort João Anes
title Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
title_short Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
title_full Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
title_fullStr Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
title_full_unstemmed Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
title_sort analysis of the oxidative stress regulon identifies <i>soxs</i> as a genetic target for resistance reversal in multidrug-resistant klebsiella pneumoniae
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/14a94f637a5743119c7891bd75fb49a9
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