NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription

Myosin VI (MVI) is known to interact with RNA Polymerase II and to play non-cytoplasmic roles in cells. Here, the authors provide evidence that the transcription co-activator NDP52 regulates MVI binding to DNA and that MVI interacts with nuclear receptors to drive gene expression.

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Auteurs principaux: Natalia Fili, Yukti Hari-Gupta, Ália dos Santos, Alexander Cook, Simon Poland, Simon M. Ameer-Beg, Maddy Parsons, Christopher P. Toseland
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/14b2334ce9e44248852b7f5d9eafede6
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