Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells

The molecular mechanisms determining the temporal identity patterns of self-renewing progenitors during cerebral development are largely unclear. Here, using single cell transcriptome analyses, the authors find progenitor temporal identity arises independent of cell-cycle progression and Notch activ...

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Autores principales:	Mayumi Okamoto, Takaki Miyata, Daijiro Konno, Hiroki R. Ueda, Takeya Kasukawa, Mitsuhiro Hashimoto, Fumio Matsuzaki, Ayano Kawaguchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/14d86c76d9cd4db3ae8082859d9eaad4
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id	oai:doaj.org-article:14d86c76d9cd4db3ae8082859d9eaad4
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spelling	oai:doaj.org-article:14d86c76d9cd4db3ae8082859d9eaad42021-12-02T17:32:38ZCell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells10.1038/ncomms113492041-1723https://doaj.org/article/14d86c76d9cd4db3ae8082859d9eaad42016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11349https://doaj.org/toc/2041-1723The molecular mechanisms determining the temporal identity patterns of self-renewing progenitors during cerebral development are largely unclear. Here, using single cell transcriptome analyses, the authors find progenitor temporal identity arises independent of cell-cycle progression and Notch activation.Mayumi OkamotoTakaki MiyataDaijiro KonnoHiroki R. UedaTakeya KasukawaMitsuhiro HashimotoFumio MatsuzakiAyano KawaguchiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mayumi Okamoto Takaki Miyata Daijiro Konno Hiroki R. Ueda Takeya Kasukawa Mitsuhiro Hashimoto Fumio Matsuzaki Ayano Kawaguchi Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
description	The molecular mechanisms determining the temporal identity patterns of self-renewing progenitors during cerebral development are largely unclear. Here, using single cell transcriptome analyses, the authors find progenitor temporal identity arises independent of cell-cycle progression and Notch activation.
format	article
author	Mayumi Okamoto Takaki Miyata Daijiro Konno Hiroki R. Ueda Takeya Kasukawa Mitsuhiro Hashimoto Fumio Matsuzaki Ayano Kawaguchi
author_facet	Mayumi Okamoto Takaki Miyata Daijiro Konno Hiroki R. Ueda Takeya Kasukawa Mitsuhiro Hashimoto Fumio Matsuzaki Ayano Kawaguchi
author_sort	Mayumi Okamoto
title	Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
title_short	Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
title_full	Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
title_fullStr	Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
title_full_unstemmed	Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
title_sort	cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/14d86c76d9cd4db3ae8082859d9eaad4
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Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells

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