A PCR amplicon-based SARS-CoV-2 replicon for antiviral evaluation

Abstract The development of specific antiviral compounds to SARS-CoV-2 is an urgent task. One of the obstacles for the antiviral development is the requirement of biocontainment because infectious SARS-CoV-2 must be handled in a biosafety level-3 laboratory. Replicon, a non-infectious self-replicati...

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Autores principales: Tomohiro Kotaki, Xuping Xie, Pei-Yong Shi, Masanori Kameoka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/14dcdbd4693243798f8fae9ed7bc5980
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