A mechanistic study on the destabilization of whole inactivated influenza virus vaccine in gastric environment.

Oral immunization using whole inactivated influenza virus vaccine promises an efficient vaccination strategy. While oral vaccination was hampered by harsh gastric environment, a systematic understanding about vaccine destabilization mechanisms was not performed. Here, we investigated the separate an...

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Détails bibliographiques
Auteurs principaux: Hyo-Jick Choi, Charles F Ebersbacher, Min-Chul Kim, Sang-Moo Kang, Carlo D Montemagno
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/14e3416410984453b32735516071269e
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