A mechanistic study on the destabilization of whole inactivated influenza virus vaccine in gastric environment.

Oral immunization using whole inactivated influenza virus vaccine promises an efficient vaccination strategy. While oral vaccination was hampered by harsh gastric environment, a systematic understanding about vaccine destabilization mechanisms was not performed. Here, we investigated the separate an...

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Autores principales: Hyo-Jick Choi, Charles F Ebersbacher, Min-Chul Kim, Sang-Moo Kang, Carlo D Montemagno
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/14e3416410984453b32735516071269e
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