Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin

Bo AhrénDepartment of Clinical Sciences, Lund University, Lund, SwedenAbstract: Inhibition of dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of glucagonlike peptide-1 (GLP-1). This increases circulating levels of active GLP-1, stimulates insulin secretion and inhibits glucag...

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Auteur principal: Bo Ahrén
Format: article
Langue:EN
Publié: Dove Medical Press 2010
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Accès en ligne:https://doaj.org/article/1553c20b118747d28cd087d966679606
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