Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE-/- mice

Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE-/- mice

Abstract Atherosclerotic plaques are characterized by an accumulation and subsequent oxidation of LDL, resulting in adaptive immune responses against formed or exposed neoepitopes of the LDL particle. Autoantibodies against native p210, the 3136–3155 amino acid sequence of the LDL protein apolipopro...

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Bibliographic Details
Main Authors: Pontus Dunér, Ingrid Yao Mattisson, Per Fogelstrand, Lars Glise, Stacey Ruiz, Christopher Farina, Jan Borén, Jan Nilsson, Eva Bengtsson
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/155b069540a744b0905d0437eeb14b5a
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