Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes

Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes

Bacillus anthracis causes the infectious disease anthrax. Here, the authors synthesized deoxy glycosides that are effective against B. anthracis and related bacteria and found that these amphiphilic compounds kill bacteria via an unusual mechanism of action.

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Autores principales: Catarina Dias, João P. Pais, Rafael Nunes, Maria-Teresa Blázquez-Sánchez, Joaquim T. Marquês, Andreia F. Almeida, Patrícia Serra, Nuno M. Xavier, Diogo Vila-Viçosa, Miguel Machuqueiro, Ana S. Viana, Alice Martins, Maria S. Santos, Ana Pelerito, Ricardo Dias, Rogério Tenreiro, Maria C. Oliveira, Marialessandra Contino, Nicola A. Colabufo, Rodrigo F. M. de Almeida, Amélia P. Rauter
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/158158d4523442a69f2881aae2aca7d4
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https://doaj.org/article/158158d4523442a69f2881aae2aca7d4

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