Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes

Bacillus anthracis causes the infectious disease anthrax. Here, the authors synthesized deoxy glycosides that are effective against B. anthracis and related bacteria and found that these amphiphilic compounds kill bacteria via an unusual mechanism of action.

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Autores principales: Catarina Dias, João P. Pais, Rafael Nunes, Maria-Teresa Blázquez-Sánchez, Joaquim T. Marquês, Andreia F. Almeida, Patrícia Serra, Nuno M. Xavier, Diogo Vila-Viçosa, Miguel Machuqueiro, Ana S. Viana, Alice Martins, Maria S. Santos, Ana Pelerito, Ricardo Dias, Rogério Tenreiro, Maria C. Oliveira, Marialessandra Contino, Nicola A. Colabufo, Rodrigo F. M. de Almeida, Amélia P. Rauter
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/158158d4523442a69f2881aae2aca7d4
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spelling oai:doaj.org-article:158158d4523442a69f2881aae2aca7d42021-12-02T17:33:15ZSugar-based bactericides targeting phosphatidylethanolamine-enriched membranes10.1038/s41467-018-06488-42041-1723https://doaj.org/article/158158d4523442a69f2881aae2aca7d42018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06488-4https://doaj.org/toc/2041-1723Bacillus anthracis causes the infectious disease anthrax. Here, the authors synthesized deoxy glycosides that are effective against B. anthracis and related bacteria and found that these amphiphilic compounds kill bacteria via an unusual mechanism of action.Catarina DiasJoão P. PaisRafael NunesMaria-Teresa Blázquez-SánchezJoaquim T. MarquêsAndreia F. AlmeidaPatrícia SerraNuno M. XavierDiogo Vila-ViçosaMiguel MachuqueiroAna S. VianaAlice MartinsMaria S. SantosAna PeleritoRicardo DiasRogério TenreiroMaria C. OliveiraMarialessandra ContinoNicola A. ColabufoRodrigo F. M. de AlmeidaAmélia P. RauterNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Catarina Dias
João P. Pais
Rafael Nunes
Maria-Teresa Blázquez-Sánchez
Joaquim T. Marquês
Andreia F. Almeida
Patrícia Serra
Nuno M. Xavier
Diogo Vila-Viçosa
Miguel Machuqueiro
Ana S. Viana
Alice Martins
Maria S. Santos
Ana Pelerito
Ricardo Dias
Rogério Tenreiro
Maria C. Oliveira
Marialessandra Contino
Nicola A. Colabufo
Rodrigo F. M. de Almeida
Amélia P. Rauter
Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
description Bacillus anthracis causes the infectious disease anthrax. Here, the authors synthesized deoxy glycosides that are effective against B. anthracis and related bacteria and found that these amphiphilic compounds kill bacteria via an unusual mechanism of action.
format article
author Catarina Dias
João P. Pais
Rafael Nunes
Maria-Teresa Blázquez-Sánchez
Joaquim T. Marquês
Andreia F. Almeida
Patrícia Serra
Nuno M. Xavier
Diogo Vila-Viçosa
Miguel Machuqueiro
Ana S. Viana
Alice Martins
Maria S. Santos
Ana Pelerito
Ricardo Dias
Rogério Tenreiro
Maria C. Oliveira
Marialessandra Contino
Nicola A. Colabufo
Rodrigo F. M. de Almeida
Amélia P. Rauter
author_facet Catarina Dias
João P. Pais
Rafael Nunes
Maria-Teresa Blázquez-Sánchez
Joaquim T. Marquês
Andreia F. Almeida
Patrícia Serra
Nuno M. Xavier
Diogo Vila-Viçosa
Miguel Machuqueiro
Ana S. Viana
Alice Martins
Maria S. Santos
Ana Pelerito
Ricardo Dias
Rogério Tenreiro
Maria C. Oliveira
Marialessandra Contino
Nicola A. Colabufo
Rodrigo F. M. de Almeida
Amélia P. Rauter
author_sort Catarina Dias
title Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
title_short Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
title_full Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
title_fullStr Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
title_full_unstemmed Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
title_sort sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/158158d4523442a69f2881aae2aca7d4
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