Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding

Protein S-sulfenylation is a posttranslational modification that can act as a sensor of redox oxidative stress. Here the authors show that, following mechanical unfolding, sulfenic acid drives disulfide bond reformation and guides non-enzymatic oxidative folding.

Saved in:
Bibliographic Details
Main Authors: Amy E. M. Beedle, Steven Lynham, Sergi Garcia-Manyes
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/15bb57049a77463cbe99c276049de68e
Tags: Add Tag
No Tags, Be the first to tag this record!