Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding

Protein S-sulfenylation is a posttranslational modification that can act as a sensor of redox oxidative stress. Here the authors show that, following mechanical unfolding, sulfenic acid drives disulfide bond reformation and guides non-enzymatic oxidative folding.

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Detalles Bibliográficos
Autores principales: Amy E. M. Beedle, Steven Lynham, Sergi Garcia-Manyes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/15bb57049a77463cbe99c276049de68e
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