Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition

Abstract Candida albicans is an opportunistic fungal pathogen colonizing the oral cavity. C. albicans secreted aspartic protease Sap6 is important for virulence during oral candidiasis since it degrades host tissues to release nutrients and essential transition metals. We found that zinc specificall...

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Autores principales: Rohitashw Kumar, Christine Breindel, Darpan Saraswat, Paul J. Cullen, Mira Edgerton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/15ddcf2dabd446da987100c3ae3d6c49
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