Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons

Chloride regulation is important for setting GABAergic reversal potential, though tools to manipulate chloride levels are limited. Here, the authors combine Archaerhodopsin with a chloride channel opsin to generate an optogenetic chloride extrusion strategy, ‘Cl-out’, which they demonstrate in hippo...

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Autores principales: Hannah Alfonsa, Jeremy H. Lakey, Robert N. Lightowlers, Andrew J. Trevelyan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/15f33b2623ff4087924ad2c757c8f991
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