Kinome-Wide RNA Interference Screening Identifies Mitogen-Activated Protein Kinases and Phosphatidylinositol Metabolism as Key Factors for Rabies Virus Infection

ABSTRACT Throughout the rabies virus (RABV) infectious cycle, host-virus interactions define its capacity to replicate, escape the immune response, and spread. As phosphorylation is a key regulatory mechanism involved in most cellular processes, kinases represent a target of choice to identify host...

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Autores principales: Benoit Besson, Seonhee Kim, Taehee Kim, Yoonae Ko, Sangchul Lee, Florence Larrous, Jihwan Song, David Shum, Regis Grailhe, Hervé Bourhy
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/160599d909b84cd9b8cf564030d9e9b1
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