Study on phylogenetic relationships, variability, and correlated mutations in M2 proteins of influenza virus A.

M2 channel, an influenza virus transmembrane protein, serves as an important target for antiviral drug design. There are still discordances concerning the role of some residues involved in proton transfer as well as the mechanism of inhibition by commercial drugs. The viral M2 proteins show high con...

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Autores principales: Ly Le, Jacek Leluk
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
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Q
Acceso en línea:https://doaj.org/article/16068c5d30314edc95c8b2c3e9a54d36
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