Three previously unrecognised classes of biosynthetic enzymes revealed during the production of xenovulene A

Xenovulene A is a fungal compound that has the potential to be used as an antidepressant. Here, the authors unravel the pathway leading to its formation in fungi and discover a new class of enzymes, which accounts for some unusual chemistry in the synthesis of xenovulene.

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Bibliographic Details
Main Authors: Raissa Schor, Carsten Schotte, Daniel Wibberg, Jörn Kalinowski, Russell J. Cox
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/16116d69ae93478dab8aee6bc00fca48
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Summary:Xenovulene A is a fungal compound that has the potential to be used as an antidepressant. Here, the authors unravel the pathway leading to its formation in fungi and discover a new class of enzymes, which accounts for some unusual chemistry in the synthesis of xenovulene.