NTRK Gene Fusion Detection in Atypical Spitz Tumors

NTRK Gene Fusion Detection in Atypical Spitz Tumors

Atypical Spitz tumors (AST) deviate from stereotypical Spitz nevi for one or more atypical features and are now regarded as an intermediate category of melanocytic tumors with uncertain malignant potential. Activating <i>NTRK1/NTRK3</i> fusions elicit oncogenic events in Spitz lesions an...

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Auteurs principaux: Rocco Cappellesso, Filippo Nozzoli, Federica Zito Marino, Sara Simi, Francesca Castiglione, Vincenzo De Giorgi, Carlo Cota, Rebecca Senetta, Giosuè Scognamiglio, Anna Maria Anniciello, Anna Maria Cesinaro, Mario Mandalà, Andrea Gianatti, Maria Gabriella Valente, Barbara Valeri, Angela Rita Sementa, Costantino Ricci, Barbara Corti, Giandomenico Roviello, Angelo Paolo Dei Tos, Renato Franco, Daniela Massi
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
atypical spitz tumor
<i>NTRK</i>
<i>NTRK1</i>
<i>NTRK3</i>
pan-TRK
Biology (General)
QH301-705.5
Chemistry
QD1-999
Accès en ligne:https://doaj.org/article/162131aa93f545a9b9095cb66dab4452
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https://doaj.org/article/162131aa93f545a9b9095cb66dab4452

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