A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease of substantial phenotypic heterogeneity in different ethnic groups. Here, using data from a multi-ethnic cohort, the authors describe an approach based on clinical and molecular data to subtype SLE patients into three clusters of severity.
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Nature Portfolio
2019
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oai:doaj.org-article:16261bd714ad43299de55c3ec9c283982021-12-02T14:35:44ZA phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus10.1038/s41467-019-11845-y2041-1723https://doaj.org/article/16261bd714ad43299de55c3ec9c283982019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11845-yhttps://doaj.org/toc/2041-1723Systemic lupus erythematosus (SLE) is an autoimmune disease of substantial phenotypic heterogeneity in different ethnic groups. Here, using data from a multi-ethnic cohort, the authors describe an approach based on clinical and molecular data to subtype SLE patients into three clusters of severity.Cristina M. LanataIshan ParanjpeJoanne NitithamKimberly E. TaylorMilena GianfrancescoManish ParanjpeShan AndrewsSharon A. ChungBrooke RheadLisa F. BarcellosLaura TrupinPatricia KatzMaria Dall’EraJinoos YazdanyMarina SirotaLindsey A. CriswellNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Cristina M. Lanata Ishan Paranjpe Joanne Nititham Kimberly E. Taylor Milena Gianfrancesco Manish Paranjpe Shan Andrews Sharon A. Chung Brooke Rhead Lisa F. Barcellos Laura Trupin Patricia Katz Maria Dall’Era Jinoos Yazdany Marina Sirota Lindsey A. Criswell A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| description |
Systemic lupus erythematosus (SLE) is an autoimmune disease of substantial phenotypic heterogeneity in different ethnic groups. Here, using data from a multi-ethnic cohort, the authors describe an approach based on clinical and molecular data to subtype SLE patients into three clusters of severity. |
| format |
article |
| author |
Cristina M. Lanata Ishan Paranjpe Joanne Nititham Kimberly E. Taylor Milena Gianfrancesco Manish Paranjpe Shan Andrews Sharon A. Chung Brooke Rhead Lisa F. Barcellos Laura Trupin Patricia Katz Maria Dall’Era Jinoos Yazdany Marina Sirota Lindsey A. Criswell |
| author_facet |
Cristina M. Lanata Ishan Paranjpe Joanne Nititham Kimberly E. Taylor Milena Gianfrancesco Manish Paranjpe Shan Andrews Sharon A. Chung Brooke Rhead Lisa F. Barcellos Laura Trupin Patricia Katz Maria Dall’Era Jinoos Yazdany Marina Sirota Lindsey A. Criswell |
| author_sort |
Cristina M. Lanata |
| title |
A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| title_short |
A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| title_full |
A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| title_fullStr |
A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| title_full_unstemmed |
A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| title_sort |
phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/16261bd714ad43299de55c3ec9c28398 |
| work_keys_str_mv |
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