TRPV2 mediates adrenomedullin stimulation of prostate and urothelial cancer cell adhesion, migration and invasion.
Adrenomedullin (AM) is a 52-amino acid peptide initially isolated from human pheochromocytoma. AM is expressed in a variety of malignant tissues and cancer cell lines and was shown to be a mitogenic factor capable of stimulating growth of several cancer cell types. In addition, AM is a survival fact...
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Auteurs principaux: | Agathe Oulidi, Alexandre Bokhobza, Dimitra Gkika, Fabien Vanden Abeele, V'yacheslav Lehen'kyi, L'houcine Ouafik, Brigitte Mauroy, Natalia Prevarskaya |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/162dc005d7224f888567a07999661e11 |
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