Dose Tailoring of Vancomycin Through Population Pharmacokinetic Modeling Among Surgical Patients in Pakistan

Dose Tailoring of Vancomycin Through Population Pharmacokinetic Modeling Among Surgical Patients in Pakistan

Background: Vancomycin is a narrow therapeutic agent, and it is necessary to optimize the dose to achieve safe therapeutic outcomes. The purpose of this study was to identify the significant covariates for vancomycin clearance and to optimize the dose among surgical patients in Pakistan.Methods: Pla...

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Autores principales: Muhammad Muaaz Munir, Huma Rasheed, Muhammad Imran Khokhar, Rizwan Rasul Khan, Hafiz Asad Saeed, Mateen Abbas, Mohsin Ali, Rabiea Bilal, Hafiz Awais Nawaz, Abdul Muqeet Khan, Shaista Qamar, Syed Muneeb Anjum, Muhammad Usman
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
vancomycin
population pharmacokinetics
Pakistan
NONMEM
dose tailoring
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/1658c40d6d364ed0938d23558238cad3
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https://doaj.org/article/1658c40d6d364ed0938d23558238cad3

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