Verification of pain-related neuromodulation mechanisms of icariin in knee osteoarthritis

Verification of pain-related neuromodulation mechanisms of icariin in knee osteoarthritis

Knee osteoarthritis (KOA) is a common disease with no specific treatment. Icariin (ICA) is considered an agent for KOA. This study aimed to confirm the pain-related neuromodulation mechanisms of ICA on KOA. Three experiments were designed: (1) verifying the therapeutic effects of ICA in vivo and in...

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Bibliographic Details
Main Authors: Xihai Li, Yunteng Xu, Hui Li, Liangliang Jia, Jie Wang, Shengxiang Liang, Aoling Cai, Xue Tan, Lili Wang, Xiaoning Wang, Yanfeng Huang, Enxiang Tao, Hongzhi Ye, Tetsuya Asakawa
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Icariin
Knee osteoarthritis
Neuropeptides
Functional magnetic resonance imaging
Virus retrograde tracing, pain-related genes
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/16868108e4de4c479a03727408b2d7dd
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https://doaj.org/article/16868108e4de4c479a03727408b2d7dd

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