Deletion of the lactoperoxidase gene causes multisystem inflammation and tumors in mice

Abstract Strongly oxidative H2O2 is biologically important, but if uncontrolled, would lead to tissue injuries. Lactoperoxidase (LPO) catalyzes the redox reaction of reducing highly reactive H2O2 to H2O while oxidizing thiocyanate (SCN−) to relatively tissue-innocuous hypothiocyanite (OSCN−). SCN− i...

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Autores principales: Jayden Yamakaze, Zhe Lu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1693411c90e147f0b61048156d38be4c
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