Acid Sphingomyelinase Controls Early Phases of Skeletal Muscle Regeneration by Shaping the Macrophage Phenotype

Acid Sphingomyelinase Controls Early Phases of Skeletal Muscle Regeneration by Shaping the Macrophage Phenotype

Skeletal muscle regeneration is a complex process involving crosstalk between immune cells and myogenic precursor cells, i.e., satellite cells. In this scenario, macrophage recruitment in damaged muscles is a mandatory step for tissue repair since pro-inflammatory M1 macrophages promote the activati...

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Autores principales: Paulina Roux-Biejat, Marco Coazzoli, Pasquale Marrazzo, Silvia Zecchini, Ilaria Di Renzo, Cecilia Prata, Alessandra Napoli, Claudia Moscheni, Matteo Giovarelli, Maria Cristina Barbalace, Elisabetta Catalani, Maria Teresa Bassi, Clara De Palma, Davide Cervia, Marco Malaguti, Silvana Hrelia, Emilio Clementi, Cristiana Perrotta
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
acid sphingomyelinase
muscle regeneration
macrophage phenotype
inflammation
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/16971eb7aebc4553b086140f94e3f576
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https://doaj.org/article/16971eb7aebc4553b086140f94e3f576

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