A distinct assembly pathway of the human 39S late pre-mitoribosome

Assembly of the mitoribosome requires assistance from numerous specialized factors. Here, structures of the human 39S late assembly intermediates identify several assembly factors which keep the 16S rRNA in immature conformations, and reveal deacylated tRNA in the ribosomal E-site, suggesting a role...

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Autores principales: Jingdong Cheng, Otto Berninghausen, Roland Beckmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/16a03bc0d75a4090929488223c675e99
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