A distinct assembly pathway of the human 39S late pre-mitoribosome

Assembly of the mitoribosome requires assistance from numerous specialized factors. Here, structures of the human 39S late assembly intermediates identify several assembly factors which keep the 16S rRNA in immature conformations, and reveal deacylated tRNA in the ribosomal E-site, suggesting a role...

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Bibliographic Details
Main Authors: Jingdong Cheng, Otto Berninghausen, Roland Beckmann
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/16a03bc0d75a4090929488223c675e99
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