Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.

Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.

c-Yes, a member of the Src tyrosine kinase family, is found highly activated in colon carcinoma but its importance relative to c-Src has remained unclear. Here we show that, in HT29 colon carcinoma cells, silencing of c-Yes, but not of c-Src, selectively leads to an increase of cell clustering assoc...

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Autores principales: Florence Sancier, Aurélie Dumont, Audrey Sirvent, Ludmilla Paquay de Plater, Thomas Edmonds, Géraldine David, Michel Jan, Catherine de Montrion, Francis Cogé, Stéphane Léonce, Michael Burbridge, Alain Bruno, Jean A Boutin, Brian Lockhart, Serge Roche, Francisco Cruzalegui
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Medicine
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Science
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Acceso en línea:https://doaj.org/article/16b8c885354a4927afa00f7e70e81214
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https://doaj.org/article/16b8c885354a4927afa00f7e70e81214

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