Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

<h4>Background</h4>Lupus erythematosus (LE) is a heterogeneous disease ranging from mainly skin-restricted manifestations (discoid LE [DLE] and subacute cutaneous LE) to a progressive multisystem disease (systemic LE [SLE]). Genetic association studies have recently identified several st...

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Autores principales: Tiina M Järvinen, Anna Hellquist, Sari Koskenmies, Elisabet Einarsdottir, Jaana Panelius, Taina Hasan, Heikki Julkunen, Leonid Padyukov, Marika Kvarnström, Marie Wahren-Herlenius, Filippa Nyberg, Mauro D'Amato, Juha Kere, Ulpu Saarialho-Kere
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/16fcc0b3ff08405e98618d322d8e4736
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