Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations.

Associations between exposures and outcomes reported in epidemiological studies are typically unadjusted for genetic confounding. We propose a two-stage approach for estimating the degree to which such observed associations can be explained by genetic confounding. First, we assess attenuation of exp...

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Autores principales: Jean-Baptiste Pingault, Frühling Rijsdijk, Tabea Schoeler, Shing Wan Choi, Saskia Selzam, Eva Krapohl, Paul F O'Reilly, Frank Dudbridge
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/1702e9f4a66d468cbb5f0b7e9f547c7e
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