Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations.
Associations between exposures and outcomes reported in epidemiological studies are typically unadjusted for genetic confounding. We propose a two-stage approach for estimating the degree to which such observed associations can be explained by genetic confounding. First, we assess attenuation of exp...
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Main Authors: | Jean-Baptiste Pingault, Frühling Rijsdijk, Tabea Schoeler, Shing Wan Choi, Saskia Selzam, Eva Krapohl, Paul F O'Reilly, Frank Dudbridge |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/1702e9f4a66d468cbb5f0b7e9f547c7e |
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