Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.

The aim of this study was to characterize the oncogenic function and mechanism of Cathepsin Z (CTSZ) at 20q13.3, a frequently amplified region in hepatocellular carcinoma (HCC). Real-time PCR were used to compare CTSZ expression between paired HCC tumor and non-tumor specimens. CTSZ gene was stably...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jian Wang, Leilei Chen, Yan Li, Xin-Yuan Guan
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/172c3607a55a4c069c47c3474900759c
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!