Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1

Satellite RNAs are aberrantly transcribed during pancreatic cancer progression. Here, the authors show that major satellite RNA binds to the multifunctional protein YBX1 in the cytoplasm and induces mutations in nuclear and mitochondrial DNA by preventing YBX1 stress-induced intracellular translocat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Takahiro Kishikawa, Motoyuki Otsuka, Takeshi Yoshikawa, Motoko Ohno, Hideaki Ijichi, Kazuhiko Koike
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/173d08df061945b9a821dd66d44d0e58
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!