Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1

Satellite RNAs are aberrantly transcribed during pancreatic cancer progression. Here, the authors show that major satellite RNA binds to the multifunctional protein YBX1 in the cytoplasm and induces mutations in nuclear and mitochondrial DNA by preventing YBX1 stress-induced intracellular translocat...

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Bibliographic Details
Main Authors: Takahiro Kishikawa, Motoyuki Otsuka, Takeshi Yoshikawa, Motoko Ohno, Hideaki Ijichi, Kazuhiko Koike
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/173d08df061945b9a821dd66d44d0e58
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